Abstract: Based on the application demands of high performance CCD imaging and high performance low-light ICCD imaging, a high performance cooling digital video CCD imaging module was developed based on CCD device of industrial level. Some design features in the imaging module such as high performance large format CCD array, low noise drive circuit, miniaturized low power consumption cooling technology and customized cooling cavity structure are introduced. It will find wide applications in military, industrial, biomedical and scientific research fields.