Abstract: In order to avoid complicated process of camera calibration and achieve the function to calibrate parameters automatically at start-up, a new method of electronic whiteboard system calibration was proposed based on CCD camera. Image pixel coordinates of reference points were extracted by using Harris corner detection algorithm. According to the basic property of projective geometry, the relationship between image pixel points and actual points was derived, and the optical center coordinates of CCD camera were obtained. The factors affecting calibration precision were analyzed, the project for decreasing calibration error was designed, and the experiment platform was constructed to calibrate parameters. Experimental results show that the calibration algorithm has simple realization and convenient application, and the calibration error of the calibration block with 1 cm length is less than 0.04 cm.