Abstract: To calibrate the optical axis consistence of airborne multi-spectral and multi-axial optoelectronic tracking device fast and accurately, a calibration system for the consistence of optical axis based on Cassegrain optical system was designed. This system used halogen lights as the visible light source, blackbody as the infrared light source, and ZnS reticle was adopted to provide infinite object. The aperture of the system was 200 mm, and the focal length was 1 500 mm. The emergent beam parallelism of points on the axis was better than 10, satisfying the demand of 1 in the test of consistence of multi-optical axis and multi-spectrum system.