Abstract: The existence of periodic moiré superlattices in moiré materials is a natural artificial quantum system. Their unique electronic energy band structures and novel physical properties make them potentially applicable in the fields of electronics and optoelectronics, and they are candidate electronic materials for extending moiré’s law. Nowadays, research on two-dimensional (2D) moiré materials has expanded from single-material systems to multivariate heterostructures, from double-layer stacking to multilayer stacking, and from fixed corner to continuously adjustable corner, providing a brand-new platform for exploring strongly correlated electron systems and topological quantum states. How to achieve large-scale, industrial-grade preparation of high-quality 2D moiré materials, investigate their intrinsic properties, and promote their applications in semiconductor technology remains an important challenge. This paper reviewed the research progress of 2D moiré materials in recent years, including preparation methods and various novel physical properties observed in experiments, and provided a summary and outlook on the current state of research in this field.