Abstract: When the size of the detection target is small and is in the far distance, due to the small field of view of the photoelectric system, the effective pre-stage target guidance is the premise for the photoelectric system to track and point the target. The essence of target guidance is converting the target point under the geodetic coordinate system into the local coordinate system of the photoelectric system. Since a series of rotational and translational parameters will be introduced in this conversion process, the accuracy of these parameters will determine the ultimate target guidance accuracy. A guidance error correction method was proposed for the photoelectric system, namely acquisition-tracking-pointing (ATP) system, based on unmanned aerial vehicle (UAV) track, which used the track data around ATP system to solve optimal parameters for coordinate conversion in the process of computing target guidance data, thereby to improve the target guidance accuracy. Experimental device built for this project achieves the following results: the azimuth guidance standard variance is better than 0.052°, the elevation guidance standard variance is better than 0.04°, and the maximum error does not exceed 0.7°. The results also show that the higher the accuracy of pre-stage guidance, the faster the target acquisition speed of ATP system, which is of great significance for improving the corresponding speed of the target disposal.