Abstract: With the development of spectroscopy technology, multi-spectral cameras have been widely used in agriculture, medical, machine vision, remote sensing and other fields. This paper proposes a miniaturized four-channel visible-waveband multi-spectral camera with a size of 107 mm×110 mm×74 mm and a mass of 1 043 g, which is especially suitable for remote sensing detection on a miniaturized drone. The camera system adopts a prism beam splitting optical path design scheme to avoid optical path difference and optical axis shift. The specially designed four-channel multi-spectral camera in visible light uses an field-programmable gate array (FPGA) controller to simultaneously drive 4 image sensors to realize four-channel pixel-level synchronous acquisition, and the exposure is exactly the same.The test results show that at the 3 specific bands of red, green and blue and the full band, the camera can output images in real time, which can output a specific band image (60 fps) or 4 band images (15 fps) at the same time, which is beneficial to the synchronous acquisition of multi-band images and the research on multi-spectral images fusion.