Abstract: In recent years, visual imaging technology has been developed rapidly, the imaging system is also improving. Single image sensor has been unable to satisfy the demand, which is the large field of view and high dynamic range. Thus, multi-camera systems with large field of view(FOV) have attracted wide attentions. Based on the principle of compound eye imaging, the multi-camera system was used to study its imaging characteristics. Considering the loss in the imaging process and the influence of the lens, the irradiance of the camera was calibrated and the vignetting was corrected. At the same time, the functions of the camera's radiation response and dark current were solved. Then the large FOV image mosaic and high dynamic range imaging of multi-camera system were carried out. Experiments show that radiometric calibration has a good influence on the above imaging.