Abstract: Aiming at the problem that the system structure of optical fiber transmission scheme of commonly used Cameralink video signal is too complicated, an optical fiber transmission scheme of the Cameralink video signal based on MAX9249 / MAX9268 was proposed.At the transmitting end, the Cameralink video signal was deserialized, encoded and serialized by using MAX9249 to obtain the optical module driving signal CML. At the receiving end, the CML signal was deserialized, decoded and serialized by using MAX9268 to obtain the Cameralink video signal, and the design and selection of optical transceiver module were detailed described.Finally, the oscilloscope was used to capture the eye diagrams of high-speed serial signals at transmitting end and receiving end. The eye diagrams of high-speed serial signals at transmitting end and receiving end are relatively clear and the eye opening degree is large. The Q factor at the transmitting end is 24.46, meeting the requirement of greater than 12 at transmitting end, while it is 8.13 at the receiving end, meeting the requirement of greater than 6. In addition, the real-time pictures acquired by the computer acquisition end has no obvious visible pixel noises after 10 minutes transmission, which proves the feasibility and effectiveness of the transmission scheme.