Abstract: In order to calibrate the optical axis parallelism of multispectral photovoltaic equipment indoor without dismantling the integrated equipment or vehicle, we designed a optical axis calibration system. The system provided a plurality of spectral bands infinity object by a multispectral collimator, realized the large span translation of collimator indoor through a twodimensional mobile platform, restored and ensured the optical axis parallelism of the collimator before and after translation using the tilt sensor, the doublelinear array charge coulped device (CCD) measurement system and the posture adjustment mechanism. The optical axis parallelism of optoelectronic equipments indoor, at different positions on vehicle with different optical axis distances and spectral bands, was calibrated by onetime. Moreover,we analyzed the design and error of the all subsystems. The results show that the system total error of the optical axis parallelism before and after translation is less than 0.142 mrad, this system can both improve the calibration accuracy and reduce the workload of the optical axes calibration. The errors of tilt sensor and position adjustment mechanism have the greatest contributions to the total system error, the system would have a higher system accuracy by selecting subsystems with higher accuracy, and could meet the requirement of more precision optical axes calibration.